Technical Research Assistant I Cellular Neuropsychiatry Lab Stem cell models of psychiatric disease
Partner's Healthcare

Job Info

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Site: The McLean Hospital Corporation

At Mass General Brigham, we know it takes a surprising range of talented professionals to advance our mission-from doctors, nurses, business people and tech experts, to dedicated researchers and systems analysts. As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community. We place great value on being a diverse, equitable and inclusive organization as we aim to reflect the diversity of the patients we serve.

At Mass General Brigham, we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore, we invite and welcome applicants from traditionally underrepresented groups in healthcare - people of color, people with disabilities, LGBTQ community, and/or gender expansive, first and second-generation immigrants, veterans, and people from different socioeconomic backgrounds - to apply.

Job Summary
McLean Hospital is a comprehensive psychiatric hospital committed to providing easy access to superior quality, cost-effective mental health services in the Boston area, Massachusetts and beyond. Since 1811, McLean Hospital has been a world leader in the treatment of mental illness and chemical dependency, research into the cause of mental illness and the training of generations of mental health care providers. McLean's multidisciplinary programs treat a broad range of psychiatric illnesses across the full continuum of care. The Laboratory of Cellular Neuropsychiatry in the Program for Neuropsychiatric Research at McLean Hospital investigates disease specific differences in two major cellular pathways: myelination and bioenergetics using induced pluripotent stem cells as a model system. This Research Assistant position supports our studies of glial abnormalities in psychiatric disease. Our work is focused on the characterization of potential mechanisms behind myelination and bioenergetic abnormalities seen in a number of psychiatric conditions. Understanding these pathways and their component parts may allow us to identify targets for therapeutics. Working under the general supervision of a Senior Technical Research Assistant, Manager or Principal Investigator and following established policies and procedures, conducts a variety of specialized experimental procedures in human iPS cell culture and differentiation, Human fibroblast culture, fluorescence microscopy, FACS analysis, cell biology assays and molecular biology techniques. Experiments, can be moderate to complex, where methodologies may need to be optimized in consultation with the lab director. Calculates, transcribes and analyzes data using basic statistics and performs literature searches. Availability for on-call duties and/or flexibility in work schedule, non-standard work week is at times necessary due to the requirements of iPS cell culture and the design of the studies. PRINCIPAL DUTIES ANDRESPONSIBILITIES: - Under general supervision, performs routine experiments, which can be moderate to complex. Experiments include mammalian tissue culture, expansion and differentiation of human induced pluripotent stem cells (hIPScs), fluorescent microscopy, and preparing special materials. - Maintains long-term tissue cultures of differentiated iPS cell lines and monitors cells for viability and contamination. - Record data, summarizes, and analyzes results using basic statistics. - Prepares laboratory reagents and chemicals. Maintains instruments and equipment. - Maintains supplies inventory in accordance with departmental procedures. - Discusses progress of work regularly with supervisor. - Performs all other duties as assigned. All McLean team members are expected to consistently demonstrate our values of integrity, compassion, respect, diversity, teamwork, excellence and innovation in their work activities and interactions.

Qualifications

SKILLS/ABILITIES/COMPETENCIES REQUIRED: - Good interpersonal and communication skills. - Good organizational skills, detail oriented. - Ability to methodically record data and to analyze data using basic statistics. - Ability to perform a variety of routine tests and prioritize work. - Knowledge of computer programs, databases, etc. - Ability to demonstrate professionalism. - Some mammalian tissue culture experience preferred QUALIFICATIONS: BS or BA in a biological/physical science with relevant course or project work required All employees must possess basic computer skills to use a variety of electronic or online systems for communication, clinical and administrative purposes.

Additional Job Details (if applicable)

Additional Job Description

Remote Type

Hybrid

Work Location

115 Mill Street

Scheduled Weekly Hours

40

Employee Type

Regular

Work Shift

Day (United States of America)

EEO Statement:

The McLean Hospital Corporation is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

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