Senior Scientist - Integrated Bioanalysis - Proteomics
Bold Disruptors. Push the boundaries of science. Fearlessly break new ground.
Are you ready to work at the cutting-edge, where scientific innovations and an entrepreneurial spirit are the norm? We're looking for dynamic thought leaders with curious minds, who are comfortable taking smart risks and constantly challenging the boundaries of science all the while learning and developing core skills and experiences.
What we do
We are a global, science-led BioPharmaceutical business and our innovative medicines are used by millions of patients worldwide.
Why we love it
The future is bright at AstraZeneca as we bring ground breaking therapies to complex disease to patients with critical needs. Scientific innovations are at the core of what we do across our industry leading portfolio which drive exciting opportunities and varied work. We're on an exciting journey to pioneer the future of healthcare!
The role
As part of the Integrated Bioanalysis (iBA) Global Team, you will be responsible for advancing the utilisation and application of arrange of -omic technics with a specific focus on using mass spectrometry applications such as proteomics, metabolomics and lipidomic applications in discovery and early development. The ideal candidate will have extensive technical expertise in developing assays and interpreting -omics for application such as pathways analysis, biomarker discovery and safety risk assessment characterization. You will be responsible for assay development, optimization, qualification, execution, and transfer of high complexity assays using state-of-art instrumentation to support pre-clinical and clinical studies. You will also contribute to tech-transfer to established CRO partners and maybe called upon to review data to ensure assay are fit for purpose including troubleshooting and data analysis. You will be expected to provide scientific leadership to junior staff and to develop strong intra and inter-departmental collaborations. You will be expected to contribute to the development of advanced bioanalytical techniques across all aspect of AZ portfolio within Oncology and Biopharma. Working with a dynamic team in a matrixed environment you will need to manage stakeholder expectations, input to project strategy and delivery while being the main interface with experienced and highly skilled bioanalytical scientist colleagues or our partnered labs. You will have the opportunity to have an immediate and lasting impact to our diverse pipeline.
The iBA group within Clinical Pharmacology and Safety Sciences provides broad discovery, preclinical, and clinical support including life cycle management across all therapeutic areas enabling pipeline delivery, decision making, innovation and advancement to improve the lives of patients through life-changing medicines.
What you'll do
You will be located at one of our research hubs (Gaithersburg MD) where you will work alongside a team of experienced bioanalytical scientists supporting a projects across our portfolio. You will also be working closely with discovery scientists across CPSS and partner line to maximise internal knowledge exchange and collaboration. You will need to use your experience and proven track record of experimental design to support delivery of robust bioanalytical data. You will also be called upon to interpret data and provide scientific insight. As a Subject Matter Expert, you will be responsible for enhancing the iBA reputation for scientific excellence by presenting at internal and external meetings, and publishing manuscripts.
The successful candidate will work closely with AstraZeneca laboratory groups within iBA and our vendor partners to ensure appropriate -omics methods are established, and we foster an environment of scientific. knowledge exchange. They will also interact with stakeholders and cross functional project teams.
Education/Experience required:
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